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| Product Category: | Knockdown Validated Polyclonal Antibody |
| Synonyms: | Retinoic Acid Receptor Gamma; Nuclear Receptor Subfamily 1 Group B Member 3; RAR-Gamma; NR1B3; Retinoic Acid Nuclear Receptor Gamma Variant 1; Retinoic Acid Nuclear Receptor Gamma Variant 2; Retinoic Acid Receptor, Gamma;RARC |
| UniProt Entry: | P13631 |
| NCBI Gene Entry: | 5916 |
| Molecular Weight: | 58 kDa |
| Clonality: | Rabbit polyclonal antibody |
| Species Reactivity: | Human |
| Applications: | WB/IC |
| Recommended Dilution: | WB 1:1000/ IC 1:200 |
| Immunogen: | Recombinant fragment of human RARG |
| Isotype: | Rabbit IgG |
| Storage Buffer: | Supplied in PBS (pH 7.5) containing 50 µg/ml BSA, 50% glycerol, and 0.01% sodium azide |
| Storage: | At –20°C |
| Background: | RARG gene encodes a retinoic acid receptor that belongs to the nuclear hormone receptor family. Retinoic acid receptors (RARs) act as ligand-dependent transcriptional regulators. When bound to ligands, RARs activate transcription by binding as heterodimers to the retinoic acid response elements (RARE) found in the promoter regions of the target genes. In their unbound form, RARs repress transcription of their target genes. RARs are involved in various biological processes, including limb bud development, skeletal growth, and matrix homeostasis. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. |
| Documents: | Please contact us to request the manual |
